- Investigate how pyroptotic cell death of microglia contributes to Alzheimer’s disease and other tauopathies using primary cell culture, mouse models and state-of-the-art techniques
- Record, analyze and present experimental data
- Contribute to scientific publications
- Manage your own research project with direct supervision by the PI
- A completed Master’s degree in Biology, Biochemistry, Molecular Biology, Cell Biology, Neurosciences or a related field
- Strong interested in disease-related research
- Proven experience working in a laboratory and research environment with a strong work ethic
- Proficiency in English is mandatory (oral and written)
- Motivated, enthusiastic person who is able to work in a team
- Experience with cell culture and/or mouse work is a plus
Working at the University Hospital Cologne and the Medical Faculty means helping to shape the future - the future of medicine, of patients and, of course, your own future. You benefit from 60 clinics and institutes as well as numerous other departments and facilities and more than 12,000 jobs. The Faculty of Medicine of the University of Cologne and the University Hospital Cologne assume important social tasks in research, teaching and patient care. A close network with many university and non-university partners guarantees an internationally successful science and the excellent education of our students.
CECAD is an inclusive, equal opportunity employer that offers attractive conditions and benefits commensurate with an international research organisation with a very collegial and family-friendly work environment.
The Ising lab is located in the CECAD Research building and as Junior Research Group part of the SFB 1403 on “Cell Death in Immunity, Inflammation and Disease" at the University of Cologne. We are investigating the role of cell death and senescence as part of the neuroinflammatory response in Alzheimer’s disease and other neurodegenerative diseases collectively termed tauopathies. Our overarching goal is to identify underlying molecular mechanisms in tauopathies to ultimately contribute to the development of new therapeutic strategies. We are combining cell culture work with mouse models, which we analyze with a multitude of techniques including but not limited to Western Blot, flow cytometry, ELISA, immunohistochemistry, secretomics and behavior tests. The project you will be working on is part of a collaborative effort within the SFB 1403 and you will get the opportunity to join and present and discuss your work in SFB meetings and seminars.